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8th Annual Conference of The ISGCT
Monday, April 22, 2013
Hadassah Hebrew University Medical Center Hadassah Auditorium, Ein-Kerem Jerusalem, Israel
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8:30 – 9:00 RECEPTION
SESSION 1 Chairpersons – Amos Panet, Jonathan Axelrod
9:00 – 9:30 Alessandro Aiuti, San Raffaele Institute for Gene Therapy, Milan, Italy Gene therapy for primary immunodeficiencies 9:30 – 9:50 Zelig Eshhar, Weizmann Institute of Science, Rehovot, Israel The T-body approach: From the mouse cage to the patient’s bed 9:50 – 10:05 Yosi Gozlan, Weizmann Institute of Science, Rehovot, Israel "First AID” for T cell gene therapy: TCR affinity maturation by somatic hypermutation
10:05 – 10:25 COFFEE BREAK 10:25 – 10:45 Michael Hayden, Teva Pharmaceutical Industries, Petah Tikva, Israel Journey from gene identification to first approved gene therapy – Story of LPL 10:45 – 11:00 Nadir Arber, Tel Aviv University, Tel Aviv, Israel Selective eradication of cancer cells by adenovirus-based delivery of cytotoxic agents: An alternative method for targeting pancreatic cancer 11:00 – 11:15 Chen Ankri, Bar-Ilan University, Ramat Gan, Israel Human T-cells engineered to express a PD1/28 costimulatory converter display enhanced anti-tumor activity 11:15 – 11:30 Shay Tayeb, Hadassah Hebrew University Medical Center, Jerusalem, Israel Newcastle Disease Virus (NDV) – A novel oncolytic agent for cancer treatment 11:30 – 11:50 Amotz Shemi, Silenseed Ltd, Jerusalem, Israel A novel RNAi-based treatment for pancreatic cancer (PC): Pre-clinical & clinical results 11:50 – 12:05 Rafi Gorodetsky, Hadassah Hebrew University Medical Center, Jerusalem, Israel Delivery of placental stromal cells by IM injections for mitigation of lethal radiation effects and enhancement of recovery from bone marrow failure
12:05 – 13:05 POSTER SESSION & LIGHT LUNCH
SESSION 2 Chairpersons - Michael Walker, Marcelle Machluf 13:05 – 13:35 Fulvio Mavilio, Genethon, Evry, France Dangerous liaisons: gene transfer vectors and the human genome 13:35 – 13:50 Hila Barash, Tel Aviv University, Tel Aviv, Israel Liver to pancreas transdifferentiation occurs in predisposed cells 13:50 – 14:05 Evelyne Zeira, Hadassah Hebrew University Medical Center, Jerusalem, Israel Reversing blindness to sight: Efficient and long-term gene delivery to the retina using the femtosecond laser 14:05 – 14:25 Dan Peer, Tel Aviv University, Tel Aviv, Israel Nanomedicines: directing the immune response?
14:25 – 14:45 COFFEE BREAK 14:45 – 15:05 Eyal Banin, Hadassah Hebrew University Medical Center, Jerusalem, Israel Phase I gene therapy trial in Israeli patients with Leber Congenital Amaurosis caused by a founder RPE65 mutation: safety and efficacy update with up to three years of follow-up 15:05 – 15:20 Niza Frankel,Tel Aviv University, Tel Aviv, Israel Derivation of oncolytic mutant HSV-1 vectors with enhanced replication in malignant cells
15:20 – 15:35 Uri Ben-David, The Hebrew University, Jerusalem, Israel High-throughput screening identifies small molecules that selectively eliminate human pluripotent stem cells and prevent teratoma formation 15:35 – 15:50 Adi Shruster, Tel Aviv University, Tel-Aviv, Israel Targeting neurogenesis in the ventral hippocampus with lentiviral Wnt3a gene transfer improves behavioral symptoms in an Alzheimer's disease model
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