Event Sponsors:
The Israeli Association for the Study of Diabetes (IASD)
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Scientific program
To download the program, click here: ACROBAT.
PROGRAM
08:00-09:00 REGISTRATION AND POSTER ASSEMBLY
09:00-09:20 OPENING AND GREETINGS
Niza Frenkel – Chairperson, Local Organizing Committee
Yoel Kloog – Dean, George S. Wise Faculty of Life Sciences
Dov Lichtenberg – Dean, Sackler Faculty of Medicine
Mina Teicher – Chief Scientist, Vice Director General, Ministry of Science
and Technology
09:20-10:00 KEYNOTE LECTURE I
Chairpersons: Eithan Galun, Ariella Oppenheim
siRNAs AND miRNAs
T Tuschl, The Rockefeller University, New York NY, USA
SESSION I GENE DELIVERY SYSTEMS
10:00-10:15 EFFICIENT TRANSDUCTION OF HIV-1 BASED VECTORS LACKING
THE ENCAPSIDATION SIGNAL
N Laham, E Bacharach, Tel Aviv University, Tel Aviv, Israel
10:15-10:30 EFFICENT TRANSGENE EXPRESSION EMPLOYING THE LYMPHOTROPIC
AMPLICON -6 DEFECTIVE VIRUS VECTORS: POTENTIAL USE FOR GENE
THERAPY AND VACCINATION
R Borenstein, A Moseri, N Frenkel, Tel Aviv University, Tel Aviv, Israel
10:30-10:45 THERAPEUTIC ULTRASOUND FOR EFFICIENT ANTI-ANGIOGENIC
GENE DELIVERY TO PROSTATE TUMORS IN-VIVO
M Duvshani-Eshet, M Machluf, Technion, Haifa, Israel
10:45-11:00 FEMTOSECOND LASER FOR DERMAL DNA DELIVERY AND
GENE EXPRESSION
E Zeira, A Manevitch, Z Manevitch, M Harati, H Yotvat, M Gropp,
O Papo, I Hemo, A Lewis, E Galun
The Hebrew University Hadassah Medical Center, Jerusalem, Israel
11:00-11:20 C O F F E E
SESSION II CANCER THERAPY
Chairpersons: Niza Frenkel, Zelig Eshhar
11:20-12:00 KEYNOTE LECTURE II
AFFINITY-DEPENDENT TARGETING AND RADIATION-CONTROLLED
EXPRESSION OF HERPES SIMPLEX VIRUS 1 IN MALIGNANT GLIOMA CELLS
B Roizman, G Zhou, The University of Chicago, Chicago IL, USA
12:00-12:25 CYTOCHROME P450 PRODRUG-BASED GENE THERAPY FOR CANCER
DJ Waxman, Y Jounaidi, C-S Chen, T Su, J Ma,
Boston University, Boston MA, USA
12:25-12:40 THE USE OF THE HSV-1 VIRION HOST SHUTOFF (vhs-1)
MUTANT FOR CANCER GENE THERAPY ONCOLYTIC VECTOR
E Noah, G Kotliroff, N Frenkel, Tel Aviv University, Tel Aviv, Israel
12:40-12:55 Microencapsulation of engineered cells secreting
antiangiogenic factors for cancer cell based therapy
L Baruch, M Machluf, Technion, Haifa, Israel
12:55-14:30 L U N C H and POSTER SESSION
14:30-14:40 MEMORIALS
Shimon Efrat: Marshall Horwitz
Smadar Cohen: Yakov Tal
SESSION III STEM CELLS
Chairpersons: Ella Naparstek, Moshe Flugelman
14:40-15:05 HUMAN EMBRYONIC STEM CELLS IN MEDICAL AND GENETIC RESEARCH
N Benvenisty, The Hebrew University, Jerusalem, Israel
15:05-15:30 TRANSPLANTATION OF GENE AND THE ENTIRE GENOME IN
CONJUNCTION WITH STEM CELL TRANSPLANTATION
S Slavin, S. Morecki
The Hebrew University Hadassah Medical Center, Jerusalem, Israel
15:30-15:45 POSTERIOR SPINAL FUSION UTILIZING NONVIRALLY ENGINEERED
FAT-DERIVED MESENCHYMAL STEM CELLS
D Sheyn, Y Zilberman, Z Gazit, D Gazit
The Hebrew University Hadassah Medical Center, Jerusalem, Israel
15:45-16:00 MODIFICATION OF NEURAL NETWORK DISCHARGE BY
TRANSPLANTATION OF GENETICALLY MODIFIED FIBROBLASTS
OVEREXPRESSING ION CHANNELS
T Bresler, D Shalhevet, R Miary, L Gerion, L Gepstein., S Marom, Y Feld
GeneGrafts Ltd, Haifa, Israel
16:00-16:20 C O F F E E
SESSION IV REGENERATIVE MEDICINE
Chairpersons: Shimon Efrat, Yossi Shaul
16:20-16:45 SMART BIOMATERIALS FOR THERAPEUTIC ANGIOGENESIS AND
TISSUE ENGINEERING
S Cohen, I Freeman, Ben-Gurion University of the Negev, Beer Sheva, Israel
16:45-17:10 MOLECULAR REPROGRAMMING OF ADULT TISSUES:
AUTOLOGOUS CELL REPLACEMENT THERAPY FOR DIABETES
S. Ferber, T. Sapir, K. Shternhal, S. Gefen-Halevy, I. Barshack, I. Ber, E. Mor,
I. Meivar-Levy,
Haim Sheba Medical Center, Tel-Hashomer, and Tel-Aviv University, Tel Aviv, Israel
17:10-17:25 BETA-CELL REPLACEMENT IN TYPE 1 DIABETES BY ENGINEERED
FETAL LIVER STEM CELLS
M Zalzman, L Anker-Kitai, S Efrat, Tel Aviv University, Tel Aviv, Israel
17:25-17:50 GENE TRANSFER AND CELL TRANSPLANTATION FOR MYOCARDIAL
ANGIOGENESIS AND FUNCTIONAL RESTORATION IN “NO OPTION”
CARDIAC PATIENTS
R Kornowski,
Rabin Medical Center, Petach Tikva, and Tel-Aviv University, Tel Aviv, Israel
17:50-18:05 INDUCTION OF ARTERIOGENESIS BY USE OF AUTOLOGOUS VENOUS
ENDOTHELIAL AND SMOOTH MUSCLE CELLS MODIFIED TO EXPRESS ANG-1
AND VEGF
M Preis, S Adawi, D Straudacher, D Lewin, B Koren, A Tsaba, Y Sarnatzki,
Y Ben-Yosef, R Shofti, J Schneiderman, T Gaspar, S Sawaed, BS Lewis, MY
Flugelman
Lady Davis Carmel Medical Center, Haifa, and MultiGene Vascular Systems Ltd.,
Israel
18:05-18:20 GENETICALLY ENGINEERED MESENCHYMAL STEM CELLS COMBINED
WITH HYBRID POLYMERIC SCAFFOLDS: A NOVEL APPROACH TO
INTERVERTEBRAL DISC REGENERATION
N Kimelman, G Pelled, RJ Oskouian, Y Zilberman, Z Gazit, D Gazit
The Hebrew University Hadassah Medical Center, Jerusalem, Israel
18:20-18:50 ISGT GENERAL ASSEMBLY
18:50 ANNOUNCEMENT OF PRIZE WINNING LECTURES & POSTERS
INVITED SPEAKERS
To download the list of invited speakers, click here: ACROBAT.
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Thomas Tuschl - Laboratory of RNA Molecular Biology, The Rockefeller University,
New York, NY USA
"siRNAs and miRNAs"
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Bernard Roizman - Departments of Microbiology, Molecular Genetics & Cell Biology,
and Biochemistry & Molecular Biology. The University of Chicago,
Chicago IL USA
"Affinity-dependent targeting and radiation-controlled expression of
herpes simplex virus 1 in malignant glioma cells"
- David Waxman- Department of Biology, Boston University, Massachusetts, USA
"Cytochrome P450 prodrug-based gene therapy for cancer"
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Nissim Benvenisty - Department of Genetics, Silberman Institute of Life Sciences,
The Hebrew University, Jerusalem, ISRAEL
"Human embryonic stem cells in medical and genetic research"
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Shimon Slavin - Bone Marrow Transplantation Unit, and the Immunology Research
Laboratory, Hadassah Medical Organization, Jerusalem, ISRAEL
"Gene therapy and whole genome therapy in conjunction with stem
cell transplantation"
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Kornowski Ran - Cardiac Catheterization Laboratories, Department of Cardiology,
Rabin Medical Center, Petach - Tikva, ISRAEL
"Intra-myocardial gene transfer to promote myocardial angiogenesis:
Basic concepts and preliminary clinical experiences"
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Smadar Cohen - Department of Medical Engineering, Ben-Gurion University of the
Negev, Beer - Sheva, ISRAEL
"Smart biomaterials and tissue engineering"
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Sarah Ferber - Department of Molecular Genetics and Biochemistry,
Sackler Faculty of Medicine and Sheba Tel Hashomer, Tel - Aviv, ISRAEL
"Regenerative medicine: Using adult tissues for generating alternate
functional organs"
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