5th Conference

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8:00                     REGISTRATION 

9:00 – 9:10         OPENING AND GREETINGS: 

                             Moshe Flugelman
                             Conference Chairman and Opening Session Chairperson
                             Ido Perlman
                             Dean – Rappaport Faculty of Medicine, Technion IIT, Haifa, Israel 
                             Aharon Swartz
                             V.P. New Ventures, TEVA Pharmaceuticals Industries
9:10 – 9:20         MEMORIAL 
                             Daniel Kornitzer
                             Rappaport Faculty of Medicine, Technion IIT, Haifa, Israel
                             In memory of Prof. Amos Oppenheim
9:20 – 9:45         KEYNOTE LECTURE I:  Kenneth Cornetta
                             Indiana University, Indianapolis, U.S.A.
                             Lentiviral vectors: Promises and challenges for clinical use
9:45 – 10:10       KEYNOTE LECTURE II: Daniel Scherman 
                             CNRS - Inserm - Genethon, Evry, France
                             Plasmid DNA electrotransfer for intracellular and secreted proteins expression: 
                             new  methodological developments and applications 

SESSION I:  STEM CELLS 
                             Chairpersons: Nathan Karin and Amos Panet

10:10 – 10:30    INVITED LECTURE I: Dov Zipori
                             Weizmann Institute of Science, Rehovot, Israel
                             Stem cells and the stem state: Relevance to cancer

10:30 – 10:50    COFFEE BREAK

10:50 – 11:05    Ran Barzilay, T Ben-Zur, S Bulvik, E Melamed, D Offen
                             Rabin Medical Center, Tel Aviv University, Sackler School of Medicine, Petah-Tikva,
                             Israel
                             Ex vivo lentiviral gene transfer of LMX1a in human bone marrow mesenchymal stem
                             cells: a novel strategy for induction of dopaminergic differentiation on adult stem cells
11:05 – 11:20    Irit Meivar-Levy, Tamar Sapir, Shiraz Gefen-Halevi, Sarah Ferber
                             Haim Sheba Medical Center, Tel-Hashomer, Israel
                             The mechanism of PDX-1 induced liver to pancreas transdifferentiation
11:20 – 11:40    INVITED LECTURE II: Belly Koren 
                             MGVS Ltd., Haifa, Israel
                             From bench to bedside: MultiGeneAngio approach
11:40 – 12:00    INVITED LECTURE III: Abraham Hochberg
                             Hebrew University, Jerusalem, Israel
                             The oncofetal H19 RNA- a new hope for cancer therapy 

SESSION II:  CANCER AND INFLAMATION GENE THERAPY
                            Chairpersons: Gideon Zamir and Eithan Galun

12:00 – 12:15   Eran Elinav, Tova Waks, Zelig Eshhar
                            Weizmann Institute of Science, Rehovot, Israel
                            Redirection of regulatory T cell specificity for the treatment of inflammatory bowel
                            disease
12:15 – 12:30   Barak Yaakov, E Eliahu, I Lazar, G Greenbaum, Z Zakay-Rones, and A. Panet
                            Hebrew University-Hadassah Medical School, Jerusalem, Israel
                            Effect of NDV-HUJ virus on Lung Cancer Cells
12:30 – 12:45   D. Uzi, V. Butin-Israeli, M. Abd-El-Latif, Yosef Haviv and Ariella Oppenheim
                            Hadassah-Hebrew University Medical School, Jerusalem, Israel
                            Recombinant viral capsid proteins attenuate acute renal failure

12:45 – 13:45   POSTER SESSION + LUNCH

13:45 – 14:05   KEYNOTE LECTURE III: Ian Graham
                            University of London, U.K.
                            Gene therapy for muscular dystrophy 

SESSION III: VECTORS
                            Chairpersons: Niza Frenkel and Sarah Ferber

14:05 – 14:20   Ronen Borenstein, Gary Guy Bushkin, Adi Museri and Niza Frenkel
                            Tel Aviv University, Tel Aviv, Israel
                            Current research of the lymphotropic HHV-6 vectors
14:20 – 14:35   Assaf C Bester and Bat Sheva Kerem
                            Hebrew University, Jerusalem, Israel
                            MLV infection confers DNA replication stress and leads to preferential integration of the
                            viral DNA into common fragile site
14:35 – 14:50   Jacob Gvili and Marcelle Machluf 
                            Technion IIT, Haifa, Israel 
                             PLGA-DNA vaccines: from targeting to efficient transfection

14:50 – 15:10   AFTERNOON COFFEE BREAK

15:10 – 15:35   KEYNOTE LECTURE IV: Volker Schirrmacher
                            German Cancer Research Center, Heidelberg, Germany
                            Newcastle Disease Virus: a promising vector for viral gene therapy of cancer 

 SESSION IV: NOVEL DELIVERY SYSTEMS 
                            Chairpersons: Shimon Marom and Michael Walker

15:35 – 15:50   Nadav Kimelman, Gadi Pelled, Yoram Zilberman, D Seliktar and Dan Gazit
                            Hebrew University-Hadassah Medical Center, Jerusalem, Israel 
                            Genetically engineered mesenchymal stem cells subjected to ex-vivo dynamic loading
                            showed enhanced osteogenic differentiation
15:50 – 16:05   Dima Sheyn, Gadi Pelled, Yoram Zilberman, Dan Gazit and Zulma Gazit
                            Hebrew University-Hadassah Medical Center Jerusalem, Israel
                            An ultrasound-based nonviral gene delivery system for bone tissue engineering in vivo
16:05 - 16:35    KEYNOTE LECTURE V: Alain Fischer
                     Hospital Necker, Assistance Publique–Hôpitaux de Paris, France
                     Gene therapy – where are we heading?

16:35 - 16:55 ISGT General Assembly